Perhaps Muslims formulated this creed out of the fear that Muhammad (who is supposed to be the final and greatest prophet) would appear inadequate in comparison to Jesus, and other Prophets of the Bible. The doctrine of Isma is contradicted by Hadith and the Qur'an.
In other words, all people are born sinners except Jesus. Muhammad is also reported as saying:
Muhammad clearly did not believe in the doctrine of Isma. What does the Qur'an say about the Prophets and sin?
Adam sinned : Sura 20:121
Noah sinned : Sura 11:47
Jonah sinned : Sura 21:87
Abraham sinned : Sura 6:76-78
Muhammad sinned : Sura 48:2
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